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TargetAdenosine receptor A2
LigandBDBM21216
Substrate/CompetitorBDBM21241
Meas. Tech.Human A1 Adenosine Receptor Binding Assay
Ki 3440±n/a nM
Citation Cosimelli, BGreco, GEhlardo, MNovellino, EDa Settimo, FTaliani, SLa Motta, CBellandi, MTuccinardi, TMartinelli, ACiampi, OTrincavelli, MLMartini, C Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists. J Med Chem51:1764-70 (2008) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Adenosine receptor A2
Name:Adenosine receptor A2
Synonyms:A2A adenosine receptor (hA2A) | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44716.46
Organism:Homo sapiens (Human)
Description:P29274
Residue:412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM21216
NameBDBM21216
Synonyms:2-[4-(ethylsulfanyl)-1H-1,3-benzodiazol-2-yl]quinoxaline | 2-[4-(ethylsulfanyl)-1H-benzimidazol-2-yl]quinoxaline | CHEMBL198008 | benzimidazole-quinoxaline, C2
TypeSmall organic molecule
Emp. Form.C17H14N4S
Mol. Mass.306.385
SMILESCCSc1cccc2nc([nH]c12)-c1cnc2ccccc2n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
BDBM21241
NameBDBM21241
Synonyms:Adenosine, N6-Ethyl-carboxamido | Adenosine-5 -(N-ethylcarboxamide) | N-Ethylcarboxamidoadenosine | [3H]NECA
Typen/a
Emp. Form.n/a
Mol. Mass.n/a
SMILESn/a
Structure