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Target
Mu-type opioid receptor
Ligand
BDBM179904
Substrate
n/a
Meas. Tech.
Opioid Receptor Binding Assay
Ki
0.050±n/a nM
Citation
 Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Methods for treating depressive symptoms US Patent  US10231963 Publication Date 3/19/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM179904
Synonyms:
US10231963, Table C.8 | US10287250, Compound D.8 | US10736890, Compound TABLE C.8 | US10752592, Compound TABLE D.8 | US11534436, Compound Table C.8 | US9133125, Table D, Compound 8 | US9656961, Example 00172
Type:
Small organic molecule
Emp. Form.:
C20H28N2O2
Mol. Mass.:
328.4485
SMILES:
C[C@H]1[C@H]2Cc3ccc(cc3[C@@]1(C)CCN2C[C@H]1CCCO1)C(N)=O |r,TLB:15:14:1:9.4.3|
Structure:
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