Target

Ligand

Substrate

Meas. Tech.

FRET Assay for LRH-1

Citation

 Whitby, RJ; Dixon, S; Maloney, PR; Delerive, P; Goodwin, BJ; Parks, DJ; Willson, TM Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1. J Med Chem 49:6652-5 (2006) [PubMed]  Article Copy BDB DOI

More Info.:

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Name:

Steroidogenic factor 1

Synonyms:

AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP

Type:

Nuclear Hormone Receptor

Mol. Mass.:

51643.43

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

461

Sequence:

MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT

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Blast E-value cutoff:

Name:

BDBM22386

Synonyms:

(3aS,6aR)-5-cyclohexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexahydropentalen-3a-amine | bicyclo[3.3.0]-oct-2-ene, 5n

Type:

Small organic molecule

Emp. Form.:

C26H31N

Mol. Mass.:

357.531

SMILES:

[H][C@]12CCC[C@@]1(Nc1ccccc1)C(=C(C2)C1CCCCC1)c1ccccc1 |r,c:15|

Structure:

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Similarity to this molecule at least:

Name:

Biotinylated DAX-1 Peptide

Synonyms:

n/a

Type:

Peptide

Mol. Mass.:

3435.91

Organism:

n/a

Description:

A peptide derived from DAX-1 amino acids 1-23.

Residue:

30

Sequence:

ITINMAGENHQWQGSILYNMLMSAKQTCNH