Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1E
Ligand
BDBM31019
Substrate
Not Available
Meas. Tech.
Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)
pH
7.4±n/a
Temperature
296.15±n/a K
EC50
2316±n/a nM
Citation
 PubChem, PC Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1E
Synonyms:
5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41697.80
Organism:
Homo sapiens (Human)
Description:
gi_112822
Residue:
365
Sequence:
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
  
Inhibitor
Name:
BDBM31019
Synonyms:
MLS000093991 | N-[2-[4-(2,3-dimethylphenyl)-1-piperazinyl]ethyl]-2-(1-ethyl-4-oxo-3-furo[3,4]pyrrolo[3,5-c][1,2,4]triazinyl)propanamide | N-[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]ethyl]-2-(1-ethyl-4-oxidanylidene-furo[3,4]pyrrolo[3,5-c][1,2,4]triazin-3-yl)propanamide | N-[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]ethyl]-2-(1-ethyl-4-oxofuro[3,4]pyrrolo[3,5-c][1,2,4]triazin-3-yl)propanamide | N-[2-[4-(2,3-dimethylphenyl)piperazino]ethyl]-2-(1-ethyl-4-keto-furo[3,4]pyrrolo[3,5-c][1,2,4]triazin-3-yl)propionamide | N-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]ethyl}-2-(5-ethyl-8-oxofuro[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)propanamide | SMR000029605 | cid_3235665
Type:
Small organic molecule
Emp. Form.:
C27H34N6O3
Mol. Mass.:
490.5973
SMILES:
CCc1nn(C(C)C(=O)NCCN2CCN(CC2)c2cccc(C)c2C)c(=O)c2cc3occc3n12
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA