BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-related protein A1
LigandBDBM33196
Substrate/CompetitorFITC-conjugated-Bim BH3 Peptide
Meas. Tech.Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1.
pH7.4±n/a
Temperature277.15±n/a K
EC50 1410±n/a nM
Citation PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1. PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:Bcl-2-like protein 5 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:Apoptosis regulator protein
Mol. Mass.:20130.01
Organism:Homo sapiens (Human)
Description:n/a
Residue:175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM33196
NameBDBM33196
Synonyms:MLS001013472 | N-[1,4-diketo-3-(o-anisidino)-2-naphthyl]acetamide | N-[3-(2-methoxyanilino)-1,4-dioxo-2-naphthalenyl]acetamide | N-[3-(2-methoxyanilino)-1,4-dioxonaphthalen-2-yl]acetamide | N-[3-[(2-methoxyphenyl)amino]-1,4-bis(oxidanylidene)naphthalen-2-yl]ethanamide | SMR000353464 | cid_284927
TypeSmall organic molecule
Emp. Form.C19H16N2O4
Mol. Mass.336.3413
SMILESCOc1ccccc1NC1=C(NC(C)=O)C(=O)c2ccccc2C1=O |c:10|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
FITC-conjugated-Bim BH3 Peptide
Name:FITC-conjugated-Bim BH3 Peptide
Synonyms:FITC-Ahx-DMRPEIWIAQELRRIGDEFNAYYAR-OH
Type:FITC-labeled Peptide
Mol. Mass.:3112.46
Organism:n/a
Description:n/a
Residue:25
Sequence:
DMRPEIWIAQELRRIGDEFNAYYAR