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Target
Bcl-2-related protein A1
Ligand
BDBM34164
Substrate
FITC-Ahx-EDIIRNIARHLAQVGDSMDR
Meas. Tech.
HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
pH
7±n/a
Temperature
296.15±n/a K
IC50
6150±0 nM
Citation
 PubChem, PC HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM34164
Synonyms:
(3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-2-quinolinone | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-carbostyril | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-quinolin-2-one | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxyquinolin-2-one | 3-[5-(4-Fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-quinolin-2-ol | MLS000071054 | SMR000015028 | cid_5423532
Type:
Small organic molecule
Emp. Form.:
C18H12FN3O3
Mol. Mass.:
337.3046
SMILES:
COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
FITC-Ahx-EDIIRNIARHLAQVGDSMDR
Synonyms:
FITC-Bid peptide
Type:
fluorescein-labeled peptide
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA