Target

Ligand

Substrate

Meas. Tech.

HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate

pH

7.4±n/a

Temperature

296.15±n/a K

Citation

 PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate PubChem Bioassay (2009)[AID] Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

Mannose-6-phosphate isomerase

Synonyms:

MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1

Type:

PROTEIN

Mol. Mass.:

46651.35

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1448919

Residue:

423

Sequence:

MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM34740

Synonyms:

4-Phenyl-naphthalen-2-ol | 4-phenyl-2-naphthalenol | 4-phenyl-2-naphthol | 4-phenylnaphthalen-2-ol | MLS000591683 | SMR000218697 | cid_1833740

Type:

Small organic molecule

Emp. Form.:

C16H12O

Mol. Mass.:

220.2659

SMILES:

Oc1cc(-c2ccccc2)c2ccccc2c1

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

Mannose-6-phosphate

Synonyms:

n/a

Type:

n/a

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA