Reaction Details Report a problem with these data
Target
Serine/threonine-protein kinase D3
Ligand
BDBM31096
Substrate
n/a
Meas. Tech.
Kinase Inhibitor Selectivity Profiling Assay
Kd
18±n/a nM
Citation
 PubChem, PC Kinase Inhibitor Selectivity Profiling Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Serine/threonine-protein kinase D3
Synonyms:
EPK2 | KPCD3_HUMAN | PRKCN | PRKD3 | Protein kinase C nu | Protein kinase C nu type | Protein kinase C, PKC | Protein kinase C, PKC; classical/novel | Protein kinase EPK2 | Serine/threonine-protein kinase D3 (PKD3) | classical/novel | nPKC-nu
Type:
Enzyme Catalytic Domain
Mol. Mass.:
100475.64
Organism:
Homo sapiens (Human)
Description:
gi_5031689
Residue:
890
Sequence:
MSANNSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDFQIRPHTLYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRRLSNVSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSLGTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFFLDPSDLDVERDEEAVKTISPSTSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGENNGDSSHNPVLAATGVGLDVAQSWEKAIRQALMPVTPQASVCTSPGQGKDHKDLSTSISVSNCQIQENVDISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGERYITHESDDARWEIHAYTHNLVYPKHFIMAPNPDDMEEDP
  
Inhibitor
Name:
BDBM31096
Synonyms:
CHEMBL290084 | Staurosporine | cid_451705
Type:
Small organic molecule
Emp. Form.:
C28H26N4O3
Mol. Mass.:
466.531
SMILES:
CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13
Structure:
Search PDB for entries with ligand similarity: