Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37078
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR
EC50
47030±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37078
Synonyms:
5-(2-methoxyphenyl)-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)isoxazole-3-carboxamide | 5-(2-methoxyphenyl)-N-(5-methyl-2-phenyl-3-pyrazolyl)-3-isoxazolecarboxamide | 5-(2-methoxyphenyl)-N-(5-methyl-2-phenyl-pyrazol-3-yl)-1,2-oxazole-3-carboxamide | 5-(2-methoxyphenyl)-N-(5-methyl-2-phenyl-pyrazol-3-yl)isoxazole-3-carboxamide | 5-(2-methoxyphenyl)-N-(5-methyl-2-phenylpyrazol-3-yl)-1,2-oxazole-3-carboxamide | MLS000087112 | SMR000023335 | cid_3243394
Type:
Small organic molecule
Emp. Form.:
C21H18N4O3
Mol. Mass.:
374.3926
SMILES:
COc1ccccc1-c1cc(no1)C(=O)Nc1cc(C)nn1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: