Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37667
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
3300±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37667
Synonyms:
4-[(E)-[4,5-diketo-1-(2-morpholinoethyl)-2-(2-thienyl)pyrrolidin-3-ylidene]-hydroxy-methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid methyl ester | 4-[(E)-hydroxy-[1-[2-(4-morpholinyl)ethyl]-4,5-dioxo-2-thiophen-2-yl-3-pyrrolidinylidene]methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid methyl ester | MLS000081406 | SMR000045473 | cid_5389834 | methyl 3,5-dimethyl-4-[(E)-[1-(2-morpholin-4-ylethyl)-4,5-bis(oxidanylidene)-2-thiophen-2-yl-pyrrolidin-3-ylidene]-oxidanyl-methyl]-1H-pyrrole-2-carboxylate | methyl 4-[(E)-hydroxy-[1-(2-morpholin-4-ylethyl)-4,5-dioxo-2-thiophen-2-ylpyrrolidin-3-ylidene]methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C23H27N3O6S
Mol. Mass.:
473.542
SMILES:
COC(=O)c1[nH]c(C)c(C(=O)C2C(N(CCN3CCOCC3)C(=O)C2=O)c2cccs2)c1C
Structure:
Search PDB for entries with ligand similarity: