Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37755
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
IC50
>66700±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37755
Synonyms:
1-(2-morpholin-4-ylethyl)-4-oxidanyl-2-phenyl-3-thiophen-2-ylcarbonyl-2H-pyrrol-5-one | 3-hydroxy-1-(2-morpholinoethyl)-5-phenyl-4-(2-thenoyl)-3-pyrrolin-2-one | 3-hydroxy-1-[2-(4-morpholinyl)ethyl]-5-phenyl-4-(2-thienylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one | 4-hydroxy-1-(2-morpholin-4-ylethyl)-2-phenyl-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one | 4-hydroxy-1-[2-(4-morpholinyl)ethyl]-3-[oxo(thiophen-2-yl)methyl]-2-phenyl-2H-pyrrol-5-one | MLS000062692 | SMR000071229 | cid_2909953
Type:
Small organic molecule
Emp. Form.:
C21H22N2O4S
Mol. Mass.:
398.475
SMILES:
O=C(C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccccc1)c1cccs1
Structure:
Search PDB for entries with ligand similarity: