Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37825
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
IC50
>66700±n/a nM
Comments
Extracted from aid = 520 and tid = 3
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37825
Synonyms:
1-Benzyl-4-(furan-2-carbonyl)-5-furan-2-yl-3-hydroxy-1,5-dihydro-pyrrol-2-one | 1-benzyl-3-(furan-2-carbonyl)-2-(furan-2-yl)-4-hydroxy-2H-pyrrol-5-one | 1-benzyl-4-(2-furoyl)-5-(2-furyl)-3-hydroxy-3-pyrrolin-2-one | 2-(2-furanyl)-3-[2-furanyl(oxo)methyl]-4-hydroxy-1-(phenylmethyl)-2H-pyrrol-5-one | 2-(furan-2-yl)-3-(furan-2-ylcarbonyl)-4-oxidanyl-1-(phenylmethyl)-2H-pyrrol-5-one | MLS000528279 | SMR000120854 | cid_3152750
Type:
Small organic molecule
Emp. Form.:
C20H15NO5
Mol. Mass.:
349.3368
SMILES:
O=C(C1C(N(Cc2ccccc2)C(=O)C1=O)c1ccco1)c1ccco1
Structure:
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