Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM38437
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM38437
Synonyms:
1-(3-acetylphenyl)-3-(3-pyridinyl)urea | 1-(3-acetylphenyl)-3-(3-pyridyl)urea | 1-(3-acetylphenyl)-3-pyridin-3-ylurea | 1-(3-ethanoylphenyl)-3-pyridin-3-yl-urea | MLS000050504 | N-(3-acetylphenyl)-N'-3-pyridinylurea | SMR000076429 | cid_978050
Type:
Small organic molecule
Emp. Form.:
C14H13N3O2
Mol. Mass.:
255.2719
SMILES:
CC(=O)c1cccc(NC(=O)Nc2cccnc2)c1
Structure:
Search PDB for entries with ligand similarity: