Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40745
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
Ki
>32400±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40745
Synonyms:
2-[4-(2-methoxyphenyl)-1-piperazinyl]-4-phenyl-6-(trifluoromethyl)pyrimidine | 2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-phenyl-6-(trifluoromethyl)pyrimidine | 2-[4-(2-methoxyphenyl)piperazino]-4-phenyl-6-(trifluoromethyl)pyrimidine | UNM000003515802 | cid_3243240
Type:
Small organic molecule
Emp. Form.:
C22H21F3N4O
Mol. Mass.:
414.4235
SMILES:
COc1ccccc1N1CCN(CC1)c1nc(cc(n1)C(F)(F)F)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: