Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40747
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
Ki
>25100±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40747
Synonyms:
2-(4-benzhydrylpiperazin-1-yl)-4-(3,4-dimethoxyphenyl)-6-(trifluoromethyl)pyrimidine | 2-(4-benzhydrylpiperazino)-4-(3,4-dimethoxyphenyl)-6-(trifluoromethyl)pyrimidine | 4-(3,4-dimethoxyphenyl)-2-[4-(diphenylmethyl)-1-piperazinyl]-6-(trifluoromethyl)pyrimidine | 4-(3,4-dimethoxyphenyl)-2-[4-(diphenylmethyl)piperazin-1-yl]-6-(trifluoromethyl)pyrimidine | UNM000003655001 | cid_16061387
Type:
Small organic molecule
Emp. Form.:
C30H29F3N4O2
Mol. Mass.:
534.5721
SMILES:
COc1ccc(cc1OC)-c1cc(nc(n1)N1CCN(CC1)C(c1ccccc1)c1ccccc1)C(F)(F)F
Structure:
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