Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40746
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
IC50
>57500±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40746
Synonyms:
2,2,2-trifluoro-1-[4-(4-phenyl-2-quinazolinyl)-1-piperazinyl]ethanone | 2,2,2-trifluoro-1-[4-(4-phenylquinazolin-2-yl)piperazin-1-yl]ethanone | 2,2,2-trifluoro-1-[4-(4-phenylquinazolin-2-yl)piperazino]ethanone | 2,2,2-tris(fluoranyl)-1-[4-(4-phenylquinazolin-2-yl)piperazin-1-yl]ethanone | UNM000003650701 | cid_1145410
Type:
Small organic molecule
Emp. Form.:
C20H17F3N4O
Mol. Mass.:
386.3704
SMILES:
FC(F)(F)C(=O)N1CCN(CC1)c1nc(-c2ccccc2)c2ccccc2n1
Structure:
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