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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41656
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor
EC50
1328±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41656
Synonyms:
4-keto-9,10-dimethoxy-2,3,6,7-tetrahydrobenzo[a]quinolizine-1-carbonitrile | 9,10-dimethoxy-4-oxidanylidene-2,3,6,7-tetrahydrobenzo[a]quinolizine-1-carbonitrile | 9,10-dimethoxy-4-oxo-2,3,6,7-tetrahydrobenzo[a]quinolizine-1-carbonitrile | 9,10-dimethoxy-4-oxo-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinoline-1-carbonitrile | MLS000097043 | SMR000075687 | cid_977094
Type:
Small organic molecule
Emp. Form.:
C16H16N2O3
Mol. Mass.:
284.3098
SMILES:
COc1cc2CCN3C(=O)CCC(C#N)=C3c2cc1OC |c:14|
Structure:
Search PDB for entries with ligand similarity: