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Target
G2/mitotic-specific cyclin-B1
Ligand
BDBM43755
Substrate
n/a
Meas. Tech.
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay (2008)[AID] 
Target
Name:
G2/mitotic-specific cyclin-B1
Synonyms:
CCNB | CCNB1 | CCNB1_HUMAN
Type:
Enzyme Subunit
Mol. Mass.:
48340.95
Organism:
Homo sapiens (Human)
Description:
P14635
Residue:
433
Sequence:
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
  
Inhibitor
Name:
BDBM43755
Synonyms:
3-hydroxy-7-phenyl-pyrrolo[3,2-e][2,1,3]benzoxadiazole | 3-hydroxy-7-phenylpyrrolo[3,2-e][2,1,3]benzoxadiazole | 3-oxidanyl-7-phenyl-pyrrolo[3,2-e][2,1,3]benzoxadiazole | 7-phenyl-6H-[1,2,5]oxadiazolo[3,4-e]indole 3-oxide | MLS000061388 | SMR000069284 | cid_690911
Type:
Small organic molecule
Emp. Form.:
C14H9N3O2
Mol. Mass.:
251.2402
SMILES:
On1onc2c1ccc1nc(cc21)-c1ccccc1
Structure:
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