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Target
G2/mitotic-specific cyclin-B1
Ligand
BDBM43770
Substrate
n/a
Meas. Tech.
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay (2008)[AID] 
Target
Name:
G2/mitotic-specific cyclin-B1
Synonyms:
CCNB | CCNB1 | CCNB1_HUMAN
Type:
Enzyme Subunit
Mol. Mass.:
48340.95
Organism:
Homo sapiens (Human)
Description:
P14635
Residue:
433
Sequence:
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
  
Inhibitor
Name:
BDBM43770
Synonyms:
(3Z)-3-(2-oxidanylidene-2-thiophen-2-yl-ethylidene)-1,4-dihydroquinoxalin-2-one | (3Z)-3-(2-oxo-2-thiophen-2-ylethylidene)-1,4-dihydroquinoxalin-2-one | (3Z)-3-[2-keto-2-(2-thienyl)ethylidene]-1,4-dihydroquinoxalin-2-one | 3-[2-oxo-2-(2-thienyl)ethylidene]-3,4-dihydro-2(1H)-quinoxalinone | MLS000705005 | SMR000230609 | cid_5410433
Type:
Small organic molecule
Emp. Form.:
C14H10N2O2S
Mol. Mass.:
270.306
SMILES:
O=C(Cc1nc2ccccc2[nH]c1=O)c1cccs1
Structure:
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