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Target
Bcl-2-like protein 2
Ligand
BDBM33110
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
4150±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33110
Synonyms:
5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-amino]-1,3-dihydro-benzoimidazol-2-one | 5-[[(E)-(6-bromo-2-keto-1-naphthylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[(Z)-(6-bromanyl-2-oxidanylidene-naphthalen-1-ylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[(Z)-(6-bromo-2-keto-1-naphthylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[(Z)-(6-bromo-2-oxo-1-naphthalenylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[(Z)-(6-bromo-2-oxonaphthalen-1-ylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one | MLS000553451 | SMR000171789 | cid_5761516
Type:
Small organic molecule
Emp. Form.:
C18H12BrN3O2
Mol. Mass.:
382.211
SMILES:
Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15|
Structure:
Search PDB for entries with ligand similarity: