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Target
Bcl-2-like protein 2
Ligand
BDBM34967
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
1810±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM34967
Synonyms:
(4E)-4-[[[4-(2-furanyl)-2-(2-methoxyethylimino)-3-thiazolyl]amino]methylidene]-2,3-dihydroxy-1-cyclohexa-2,5-dienone | (4E)-4-[[[4-(2-furyl)-2-(2-methoxyethylimino)-4-thiazolin-3-yl]amino]methylene]-2,3-dihydroxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[[4-(furan-2-yl)-2-(2-methoxyethylimino)-1,3-thiazol-3-yl]amino]methylidene]-2,3-bis(oxidanyl)cyclohexa-2,5-dien-1-one | (4E)-4-[[[4-(furan-2-yl)-2-(2-methoxyethylimino)-1,3-thiazol-3-yl]amino]methylidene]-2,3-dihydroxycyclohexa-2,5-dien-1-one | MLS000774542 | SMR000372065 | cid_6040412
Type:
Small organic molecule
Emp. Form.:
C17H17N3O5S
Mol. Mass.:
375.399
SMILES:
COCCN=c1scc(-c2ccco2)n1N=Cc1ccc(O)c(O)c1O |w:15.16,4.3|
Structure:
Search PDB for entries with ligand similarity: