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Target
Alkaline phosphatase, germ cell type
Ligand
BDBM41895
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation
IC50
374±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM41895
Synonyms:
(3E)-3-[[2-(3,4-dihydroxyphenyl)ethylamino]methylene]oxindole | (3E)-3-[[2-(3,4-dihydroxyphenyl)ethylamino]methylidene]-1H-indol-2-one | (3E)-3-[[2-[3,4-bis(oxidanyl)phenyl]ethylamino]methylidene]-1H-indol-2-one | MLS-0390859.0001 | cid_5922288
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3
Mol. Mass.:
296.3205
SMILES:
Oc1ccc(CCN=CC2C(=O)Nc3ccccc23)cc1O |w:7.6|
Structure:
Search PDB for entries with ligand similarity: