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Target
Regulator of G-protein signaling 16
Ligand
BDBM47779
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47779
Synonyms:
2-furanyl-[4-[3-(4-morpholinyl)-4-nitrophenyl]-1-piperazinyl]methanone | 2-furyl-[4-(3-morpholino-4-nitro-phenyl)piperazino]methanone | MLS000711509 | SMR000281276 | cid_2894898 | furan-2-yl-[4-(3-morpholin-4-yl-4-nitro-phenyl)piperazin-1-yl]methanone | furan-2-yl-[4-(3-morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]methanone
Type:
Small organic molecule
Emp. Form.:
C19H22N4O5
Mol. Mass.:
386.4018
SMILES:
[O-][N+](=O)c1ccc(cc1N1CCOCC1)N1CCN(CC1)C(=O)c1ccco1
Structure:
Search PDB for entries with ligand similarity: