Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48122
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
13100±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48122
Synonyms:
5-bromanyl-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-6-oxidanylidene-pyran-3-carboxamide | 5-bromo-6-keto-N-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)pyran-3-carboxamide | 5-bromo-N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-6-oxo-3-pyrancarboxamide | 5-bromo-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-6-oxopyran-3-carboxamide | MLS000036865 | SMR000037750 | cid_661972
Type:
Small organic molecule
Emp. Form.:
C17H14BrN3O4
Mol. Mass.:
404.215
SMILES:
Cc1c(NC(=O)c2coc(=O)c(Br)c2)c(=O)n(-c2ccccc2)n1C
Structure:
Search PDB for entries with ligand similarity: