Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM37077
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
670±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM37077
Synonyms:
4-[[7-(diethylamino)-2-keto-chromen-3-yl]amino]-4-keto-butyric acid | 4-[[7-(diethylamino)-2-oxidanylidene-chromen-3-yl]amino]-4-oxidanylidene-butanoic acid | 4-[[7-(diethylamino)-2-oxo-1-benzopyran-3-yl]amino]-4-oxobutanoic acid | 4-[[7-(diethylamino)-2-oxochromen-3-yl]amino]-4-oxobutanoic acid | 4-{[7-(diethylamino)-2-oxo-2H-chromen-3-yl]amino}-4-oxobutanoic acid | MLS000089659 | SMR000024277 | cid_3243384
Type:
Small organic molecule
Emp. Form.:
C17H20N2O5
Mol. Mass.:
332.3511
SMILES:
CCN(CC)c1ccc2cc(NC(=O)CCC(O)=O)c(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: