Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM39069
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
230±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM39069
Synonyms:
(Z)-3-(1,3-benzodioxol-5-ylamino)-1-(2-pyridinyl)-2-propen-1-one | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-(2-pyridyl)prop-2-en-1-one | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-pyridin-2-yl-prop-2-en-1-one | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-pyridin-2-ylprop-2-en-1-one | MLS000108346 | SMR000104305 | cid_5310753
Type:
Small organic molecule
Emp. Form.:
C15H12N2O3
Mol. Mass.:
268.2674
SMILES:
O=C(CC=Nc1ccc2OCOc2c1)c1ccccn1 |w:4.4|
Structure:
Search PDB for entries with ligand similarity: