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TargetInduced myeloid leukemia cell differentiation protein Mcl-1
LigandBDBM33196
Substrate/Competitorn/a
Meas. Tech.Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors
IC50 2276.162697±n/a nM
Citation PubChem, PC Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Induced myeloid leukemia cell differentiation protein Mcl-1
Name:Induced myeloid leukemia cell differentiation protein Mcl-1
Synonyms:Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT
Type:Membrane; Single-pass membrane protein
Mol. Mass.:37332.87
Organism:Homo sapiens (Human)
Description:n/a
Residue:350
Sequence:
MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
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  Blast E-value cutoff:
BDBM33196
NameBDBM33196
Synonyms:MLS001013472 | N-[1,4-diketo-3-(o-anisidino)-2-naphthyl]acetamide | N-[3-(2-methoxyanilino)-1,4-dioxo-2-naphthalenyl]acetamide | N-[3-(2-methoxyanilino)-1,4-dioxonaphthalen-2-yl]acetamide | N-[3-[(2-methoxyphenyl)amino]-1,4-bis(oxidanylidene)naphthalen-2-yl]ethanamide | SMR000353464 | cid_284927
TypeSmall organic molecule
Emp. Form.C19H16N2O4
Mol. Mass.336.3413
SMILESCOc1ccccc1NC1=C(NC(C)=O)C(=O)c2ccccc2C1=O |c:10|
Structure
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n/a