Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51534
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
4565±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51534
Synonyms:
(2-oxidanylideneoxolan-3-yl) 1-(4-fluorophenyl)-3-methyl-thieno[2,3-c]pyrazole-5-carboxylate | (2-oxooxolan-3-yl) 1-(4-fluorophenyl)-3-methylthieno[2,3-c]pyrazole-5-carboxylate | 1-(4-fluorophenyl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxylic acid (2-oxo-3-oxolanyl) ester | 1-(4-fluorophenyl)-3-methyl-thieno[2,3-c]pyrazole-5-carboxylic acid (2-ketotetrahydrofuran-3-yl) ester | MLS000058712 | SMR000067217 | cid_2999178
Type:
Small organic molecule
Emp. Form.:
C17H13FN2O4S
Mol. Mass.:
360.36
SMILES:
Cc1nn(-c2ccc(F)cc2)c2sc(cc12)C(=O)OC1CCOC1=O
Structure:
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