Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM49127
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
13207±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM49127
Synonyms:
2-(2-furanyl)-N-(2-oxolanylmethyl)-4-quinolinecarboxamide | 2-(2-furyl)-N-(tetrahydrofurfuryl)cinchoninamide | 2-(furan-2-yl)-N-(oxolan-2-ylmethyl)quinoline-4-carboxamide | MLS000081670 | SMR000062907 | cid_2999584
Type:
Small organic molecule
Emp. Form.:
C19H18N2O3
Mol. Mass.:
322.3578
SMILES:
O=C(NCC1CCCO1)c1cc(nc2ccccc12)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: