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Target
Zinc finger protein mex-5
Ligand
BDBM52209
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52209
Synonyms:
2-amino-5-keto-4-phenyl-4,6,7,8-tetrahydrochromene-3-carbonitrile | 2-amino-5-oxo-4-phenyl-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile | 2-amino-5-oxo-4-phenyl-4,6,7,8-tetrahydrochromene-3-carbonitrile | 2-azanyl-5-oxidanylidene-4-phenyl-4,6,7,8-tetrahydrochromene-3-carbonitrile | MLS000105493 | SMR000102374 | cid_605218
Type:
Small organic molecule
Emp. Form.:
C16H14N2O2
Mol. Mass.:
266.2946
SMILES:
N=C1OC2=C(C(C1C#N)c1ccccc1)C(=O)CCC2 |c:3|
Structure:
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