Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52478
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
14647±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52478
Synonyms:
3-(1,3-benzothiazol-2-ylsulfanyl)-N'-[(Z)-(2-oxidanylidenenaphthalen-1-ylidene)methyl]propanehydrazide | 3-(1,3-benzothiazol-2-ylsulfanyl)-N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]propanehydrazide | 3-(1,3-benzothiazol-2-ylthio)-N'-[(Z)-(2-keto-1-naphthylidene)methyl]propionohydrazide | 3-(1,3-benzothiazol-2-ylthio)-N'-[(Z)-(2-oxo-1-naphthalenylidene)methyl]propanehydrazide | 3-(Benzothiazol-2-ylsulfanyl)-propionic acid [1-(2-hydroxy-naphthalen-1-yl)-meth-(E)-ylidene]-hydrazide | MLS000591355 | SMR000218975 | cid_6504438
Type:
Small organic molecule
Emp. Form.:
C21H17N3O2S2
Mol. Mass.:
407.509
SMILES:
Oc1ccc2ccccc2c1C=NNC(=O)CCSc1nc2ccccc2s1 |w:12.14|
Structure:
Search PDB for entries with ligand similarity: