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Target
Zinc finger protein mex-5
Ligand
BDBM53275
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM53275
Synonyms:
1-(2-furanylmethyl)-3-[2-furanyl(oxo)methyl]-4-hydroxy-2-(3-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 3-(furan-2-carbonyl)-1-(furan-2-ylmethyl)-4-hydroxy-2-(3-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 3-(furan-2-ylcarbonyl)-1-(furan-2-ylmethyl)-4-oxidanyl-2-(3-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 5-(3-Allyloxy-phenyl)-4-(furan-2-carbonyl)-1-furan-2-ylmethyl-3-hydroxy-1,5-dihydro-pyrrol-2-one | 5-(3-allyloxyphenyl)-1-(2-furfuryl)-4-(2-furoyl)-3-hydroxy-3-pyrrolin-2-one | MLS001221369 | SMR000612387 | cid_3154084
Type:
Small organic molecule
Emp. Form.:
C23H19NO6
Mol. Mass.:
405.4001
SMILES:
C=CCOc1cccc(c1)C1C(C(=O)c2ccco2)C(=O)C(=O)N1Cc1ccco1
Structure:
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