Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM53330
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM53330
Synonyms:
(5-bromanylthiophen-2-yl)-(4-pyridin-2-ylpiperazin-1-yl)methanone | (5-bromo-2-thienyl)-[4-(2-pyridyl)piperazino]methanone | (5-bromo-2-thiophenyl)-[4-(2-pyridinyl)-1-piperazinyl]methanone | (5-bromothiophen-2-yl)-(4-pyridin-2-ylpiperazin-1-yl)methanone | MLS001223739 | SMR000679670 | cid_1246464
Type:
Small organic molecule
Emp. Form.:
C14H14BrN3OS
Mol. Mass.:
352.249
SMILES:
Brc1ccc(s1)C(=O)N1CCN(CC1)c1ccccn1
Structure:
Search PDB for entries with ligand similarity: