Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52863
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
31704±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52863
Synonyms:
6-Oxo-1,6-dihydro-pyridazine-3-carboxylic acid [1-(2-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide | 6-keto-N'-[(E)-(6-keto-5-methoxy-cyclohexa-2,4-dien-1-ylidene)methyl]-1H-pyridazine-3-carbohydrazide | MLS000777445 | N'-[(E)-(5-methoxy-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)methyl]-6-oxidanylidene-1H-pyridazine-3-carbohydrazide | N'-[(E)-(5-methoxy-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-6-oxo-1H-pyridazine-3-carbohydrazide | N'-[(E)-(5-methoxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-6-oxo-1H-pyridazine-3-carbohydrazide | SMR000413839 | cid_5424318
Type:
Small organic molecule
Emp. Form.:
C13H12N4O4
Mol. Mass.:
288.2588
SMILES:
COc1cccc(C=NNC(=O)c2ccc(=O)[nH]n2)c1O |w:8.8|
Structure:
Search PDB for entries with ligand similarity: