Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM47991
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
229546±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM47991
Synonyms:
(3Z)-6-chloranyl-3-(2-oxidanylidene-2-thiophen-2-yl-ethylidene)-4H-1,4-benzoxazin-2-one | (3Z)-6-chloro-3-(2-oxo-2-thiophen-2-ylethylidene)-4H-1,4-benzoxazin-2-one | (3Z)-6-chloro-3-[2-keto-2-(2-thienyl)ethylidene]-4H-1,4-benzoxazin-2-one | 6-Chloro-3-[2-oxo-2-thiophen-2-yl-eth-(E)-ylidene]-3,4-dihydro-benzo[1,4]oxazin-2-one | MLS000769456 | SMR000434169 | cid_5614757
Type:
Small organic molecule
Emp. Form.:
C14H8ClNO3S
Mol. Mass.:
305.736
SMILES:
Clc1ccc2oc(=O)c(CC(=O)c3cccs3)nc2c1
Structure:
Search PDB for entries with ligand similarity: