Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52881
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
41641±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52881
Synonyms:
(3-butyl-7-methyl-6,8-dioxoisochromen-7-yl) 3-phenylpropanoate | 3-phenylpropanoic acid (3-butyl-7-methyl-6,8-dioxo-2-benzopyran-7-yl) ester | 3-phenylpropionic acid (3-butyl-6,8-diketo-7-methyl-isochromen-7-yl) ester | CMLD003367 | MLS000438292 | SMR000452561 | [3-butyl-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] 3-phenylpropanoate | cid_16745546
Type:
Small organic molecule
Emp. Form.:
C23H24O5
Mol. Mass.:
380.4337
SMILES:
CCCCC1=CC2=CC(=O)C(C)(OC(=O)CCc3ccccc3)C(=O)C2=CO1 |c:27,t:4,6|
Structure:
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