Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52926
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52926
Synonyms:
(3Z)-3-[(2-methyl-1H-imidazol-5-yl)methylene]oxindole | (3Z)-3-[(2-methyl-1H-imidazol-5-yl)methylidene]-1H-indol-2-one | 3-[(Z)-(2-methyl-1H-imidazol-4-yl)methylidene]-1H-indol-2-one | MLS000834757 | SMR000458375 | cid_5714575
Type:
Small organic molecule
Emp. Form.:
C13H11N3O
Mol. Mass.:
225.2459
SMILES:
Cc1ncc(C=C2C(=O)Nc3ccccc23)[nH]1 |w:5.4|
Structure:
Search PDB for entries with ligand similarity: