Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM53304
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM53304
Synonyms:
1-[(4-ethyl-5-methyl-thiophen-3-yl)carbonylamino]-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea | 1-[(4-ethyl-5-methyl-thiophene-3-carbonyl)amino]-3-[4-(2-pyrimidylsulfamoyl)phenyl]thiourea | 1-[(4-ethyl-5-methylthiophene-3-carbonyl)amino]-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea | 1-[[(4-ethyl-5-methyl-3-thiophenyl)-oxomethyl]amino]-3-[4-(2-pyrimidinylsulfamoyl)phenyl]thiourea | MLS001035818 | SMR000666376 | cid_2206972
Type:
Small organic molecule
Emp. Form.:
C19H20N6O3S3
Mol. Mass.:
476.595
SMILES:
CCc1c(C)scc1C(=O)NNC(=S)Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1
Structure:
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