Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM53394
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM53394
Synonyms:
4-[(7H-purin-6-ylhydrazo)methylidene]-1-cyclohexa-2,5-dienone | 4-[[2-(7H-purin-6-yl)hydrazinyl]methylidene]cyclohexa-2,5-dien-1-one | 4-[[N'-(7H-purin-6-yl)hydrazino]methylene]cyclohexa-2,5-dien-1-one | MLS000419002 | SMR000320358 | cid_5803687
Type:
Small organic molecule
Emp. Form.:
C12H10N6O
Mol. Mass.:
254.2474
SMILES:
Oc1ccc(CN=Nc2ncnc3nc[nH]c23)cc1 |w:7.7|
Structure:
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