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Target
M1 family aminopeptidase
Ligand
BDBM53644
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP)
IC50
51060±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) PubChem Bioassay (2008)[AID] 
Target
Name:
M1 family aminopeptidase
Synonyms:
AMPN_PLAF7 | M1AAP | Zinc aminopeptidase | m1-family aminopeptidase
Type:
PROTEIN
Mol. Mass.:
126072.31
Organism:
Plasmodium falciparum (isolate FcB1 / Columbia)
Description:
ChEMBL_735637
Residue:
1085
Sequence:
MKLTKGCAYKYIIFTVLILANILYDNKKRCMIKKNLRISSCGIISRLLKSNSNYNSFNKNYNFTSAISELQFSNFWNLDILQKDIFSNIHNNKNKPQSYIIHKRLMSEKGDNNNNNHQNNNGNDNKKRLGSVVNNEENTCSDKRMKPFEEGHGITQVDKMNNNSDHLQQNGVMNLNSNNVENNNNNNSVVVKKNEPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVYLPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLDTKRQELMLNEMNTMLQEPNISNNLKEYLLRLTNKL
  
Inhibitor
Name:
BDBM53644
Synonyms:
2-[4-[(1-tert-amyltetrazol-5-yl)-(6-quinolyl)methyl]piperazino]-1,3-benzothiazole | 2-[4-[[1-(2-methylbutan-2-yl)-1,2,3,4-tetrazol-5-yl]-quinolin-6-yl-methyl]piperazin-1-yl]-1,3-benzothiazole | 2-[4-[[1-(2-methylbutan-2-yl)-5-tetrazolyl]-(6-quinolinyl)methyl]-1-piperazinyl]-1,3-benzothiazole | 2-[4-[[1-(2-methylbutan-2-yl)tetrazol-5-yl]-quinolin-6-ylmethyl]piperazin-1-yl]-1,3-benzothiazole | 6-{(4-Benzothiazol-2-yl-piperazin-1-yl)-[1-(1,1-dimethyl-propyl)-1H-tetrazol-5-yl]-methyl}-quinoline | MLS000034621 | SMR000003953 | cid_647101
Type:
Small organic molecule
Emp. Form.:
C27H30N8S
Mol. Mass.:
498.646
SMILES:
CCC(C)(C)n1nnnc1C(N1CCN(CC1)c1nc2ccccc2s1)c1ccc2ncccc2c1
Structure:
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