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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM54907
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
1870±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM54907
Synonyms:
2-Amino-1-phenethyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylic acid (furan-2-ylmethyl)-amide | 2-amino-N-(2-furanylmethyl)-1-(2-phenylethyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-amino-N-(2-furfuryl)-1-phenethyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-(furan-2-ylmethyl)-1-(2-phenylethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-azanyl-N-(furan-2-ylmethyl)-1-(2-phenylethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000595296 | SMR000149819 | cid_1912988
Type:
Small organic molecule
Emp. Form.:
C24H21N5O2
Mol. Mass.:
411.4558
SMILES:
Nc1c(C(=O)NCc2ccco2)c2nc3ccccc3nc2n1CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: