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TargetNS3
LigandBDBM55049
Substrate/Competitorn/a
Meas. Tech.Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3).
IC50 12218±n/a nM
Citation PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
NS3
Name:NS3
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:67067.41
Organism:Hepatitis C virus
Description:gi_125541954
Residue:631
Sequence:
APITAYAQQTRGLLGCIITGLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASSKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRG
DGRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVEGLETTMR
SPVFSDNSSPPAVPQSYQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGA
YMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGSAYDIIICDECHSTDATSI
LGIGTVLDQAETAGARLTVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEAIK
GGRHLIFCHSKKKCDELAAKLVALGVNAVAYYRGLDVSVIPASGDVVVVATDALMTGFTG
DFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVTPGE
RPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLT
HIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLY
RLGAVQNEITLTHPITKYIMTCMSADLEVVT
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  Blast E-value cutoff:
BDBM55049
NameBDBM55049
Synonyms:MLS001212293 | N-[N'-(2-Butoxy-benzoyl)-hydrazinocarbothioyl]-2-nitro-benzamide | N-[[(2-butoxybenzoyl)amino]carbamothioyl]-2-nitrobenzamide | N-[[(2-butoxybenzoyl)amino]thiocarbamoyl]-2-nitro-benzamide | N-[[(2-butoxyphenyl)carbonylamino]carbamothioyl]-2-nitro-benzamide | N-[[[(2-butoxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamide | SMR000517402 | cid_3138378
TypeSmall organic molecule
Emp. Form.C19H20N4O5S
Mol. Mass.416.451
SMILESCCCCOc1ccccc1C(=O)NNC(=S)NC(=O)c1ccccc1[N+]([O-])=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a