Reaction Details Report a problem with these data
Target
Neutrophil cytosol factor 1 [S99G]
Ligand
BDBM55662
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
IC50
50000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay (2008)[AID] 
Target
Name:
Neutrophil cytosol factor 1 [S99G]
Synonyms:
NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44664.39
Organism:
Homo sapiens (Human)
Description:
gi_115298672
Residue:
390
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
  
Inhibitor
Name:
BDBM55662
Synonyms:
4-bromanyl-N-(2-ethoxyphenyl)-2-methyl-pyrazole-3-carboxamide | 4-bromo-2-methyl-N-o-phenetyl-pyrazole-3-carboxamide | 4-bromo-N-(2-ethoxyphenyl)-1-methyl-1H-pyrazole-5-carboxamide | 4-bromo-N-(2-ethoxyphenyl)-2-methyl-3-pyrazolecarboxamide | 4-bromo-N-(2-ethoxyphenyl)-2-methylpyrazole-3-carboxamide | MLS000699186 | SMR000227214 | cid_903277
Type:
Small organic molecule
Emp. Form.:
C13H14BrN3O2
Mol. Mass.:
324.173
SMILES:
CCOc1ccccc1NC(=O)c1c(Br)cnn1C
Structure:
Search PDB for entries with ligand similarity: