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Target
Kallikrein-5
Ligand
BDBM45437
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
50000±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM45437
Synonyms:
2-[[1-(4-chloro-2,5-dimethyl-phenyl)sulfonylprolyl]amino]propionic acid methyl ester | 2-[[[1-(4-chloro-2,5-dimethylphenyl)sulfonyl-2-pyrrolidinyl]-oxomethyl]amino]propanoic acid methyl ester | MLS000113797 | SMR000109689 | cid_2930409 | methyl 2-[[1-(4-chloranyl-2,5-dimethyl-phenyl)sulfonylpyrrolidin-2-yl]carbonylamino]propanoate | methyl 2-[[1-(4-chloro-2,5-dimethylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoate
Type:
Small organic molecule
Emp. Form.:
C17H23ClN2O5S
Mol. Mass.:
402.893
SMILES:
COC(=O)C(C)NC(=O)C1CCCN1S(=O)(=O)c1cc(C)c(Cl)cc1C
Structure:
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