Reaction Details Report a problem with these data
Target
M17 leucyl aminopeptidase
Ligand
BDBM60026
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)
IC50
56570±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay (2009)[AID] 
Target
Name:
M17 leucyl aminopeptidase
Synonyms:
leucine aminopeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
67834.32
Organism:
Plasmodium falciparum 3D7
Description:
gi_124809582
Residue:
605
Sequence:
MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKKNINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFNDNKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLETLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPENVEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSKYADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLNDAL
  
Inhibitor
Name:
BDBM60026
Synonyms:
3-methyl-N-[(2-phenylethanoylamino)carbamothioyl]benzamide | 3-methyl-N-[[(1-oxo-2-phenylethyl)hydrazo]-sulfanylidenemethyl]benzamide | 3-methyl-N-[[(2-phenylacetyl)amino]carbamothioyl]benzamide | 3-methyl-N-[[(2-phenylacetyl)amino]thiocarbamoyl]benzamide | 3-methyl-N-{[2-(phenylacetyl)hydrazino]carbothioyl}benzamide | MLS000704240 | SMR000228691 | cid_3912472
Type:
Small organic molecule
Emp. Form.:
C17H17N3O2S
Mol. Mass.:
327.401
SMILES:
Cc1cccc(c1)C(=O)NC(=S)NNC(=O)Cc1ccccc1
Structure:
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