Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM48679
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
9377±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM48679
Synonyms:
2-[(4-chlorophenyl)hydrazinylidene]-3-oxidanylidene-3-phenyl-propanenitrile | 2-[(4-chlorophenyl)hydrazinylidene]-3-oxo-3-phenylpropanenitrile | 2-[(4-chlorophenyl)hydrazono]-3-keto-3-phenyl-propionitrile | 2-[(4-chlorophenyl)hydrazono]-3-oxo-3-phenylpropanenitrile | MLS000545160 | N-(4-chloroanilino)-2-oxo-2-phenylethanimidoyl cyanide | SMR000163064 | cid_830566
Type:
Small organic molecule
Emp. Form.:
C15H10ClN3O
Mol. Mass.:
283.712
SMILES:
Clc1ccc(NN=C(C#N)C(=O)c2ccccc2)cc1 |w:6.5|
Structure:
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