Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM46413
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
11573±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM46413
Synonyms:
2-benzyl-5-(4-bromophenyl)pyrazol-3-amine | 5-(4-bromophenyl)-2-(phenylmethyl)-3-pyrazolamine | 5-(4-bromophenyl)-2-(phenylmethyl)pyrazol-3-amine | MLS000712366 | SMR000282133 | [2-benzyl-5-(4-bromophenyl)pyrazol-3-yl]amine | cid_693933
Type:
Small organic molecule
Emp. Form.:
C16H14BrN3
Mol. Mass.:
328.206
SMILES:
Nc1cc(nn1Cc1ccccc1)-c1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: