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TargetHsf1 protein
LigandBDBM52218
Substrate/Competitorn/a
Meas. Tech.Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50>195000±0 nM
Citation PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hsf1 protein
Name:Hsf1 protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:57208.68
Organism:Mus musculus
Description:P38532
Residue:525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM52218
NameBDBM52218
Synonyms:2-amino-5-keto-7,7-dimethyl-4-phenyl-6,8-dihydro-4H-chromene-3-carbonitrile | 2-amino-7,7-dimethyl-5-oxo-4-phenyl-6,8-dihydro-4H-1-benzopyran-3-carbonitrile | 2-amino-7,7-dimethyl-5-oxo-4-phenyl-6,8-dihydro-4H-chromene-3-carbonitrile | 2-azanyl-7,7-dimethyl-5-oxidanylidene-4-phenyl-6,8-dihydro-4H-chromene-3-carbonitrile | MLS000105495 | SMR000102376 | cid_2737879
TypeSmall organic molecule
Emp. Form.C18H18N2O2
Mol. Mass.294.3477
SMILESCC1(C)CC(=O)C2=C(C1)OC(=N)C(C#N)C2c1ccccc1 |c:6|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a