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Target
Heat shock factor protein 1
Ligand
BDBM63310
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50
>195000±0 nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM63310
Synonyms:
MLS000418008 | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-keto-chromene-3-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxidanylidene-chromene-3-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxo-1-benzopyran-3-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxochromene-3-carboxamide | SMR000264804 | cid_2395074
Type:
Small organic molecule
Emp. Form.:
C18H13NO5
Mol. Mass.:
323.2995
SMILES:
O=C(Nc1ccc2OCCOc2c1)c1coc2ccccc2c1=O
Structure:
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