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TargetHsf1 protein
LigandBDBM63494
Substrate/Competitorn/a
Meas. Tech.Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50>195000±0 nM
Citation PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hsf1 protein
Name:Hsf1 protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:57208.68
Organism:Mus musculus
Description:P38532
Residue:525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
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  Blast E-value cutoff:
BDBM63494
NameBDBM63494
Synonyms:2-[1-(phenylmethyl)-4-[(3-pyrazol-1-ylphenyl)methyl]piperazin-2-yl]ethanol | 2-[1-(phenylmethyl)-4-[[3-(1-pyrazolyl)phenyl]methyl]-2-piperazinyl]ethanol | 2-[1-benzyl-4-(3-pyrazol-1-ylbenzyl)piperazin-2-yl]ethanol | 2-[1-benzyl-4-[(3-pyrazol-1-ylphenyl)methyl]piperazin-2-yl]ethanol | 2-{1-benzyl-4-[3-(1H-pyrazol-1-yl)benzyl]piperazin-2-yl}ethanol | MLS000733157 | SMR000315181 | cid_16190658
TypeSmall organic molecule
Emp. Form.C23H28N4O
Mol. Mass.376.4946
SMILESOCCC1CN(Cc2cccc(c2)-n2cccn2)CCN1Cc1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a